UBC researchers develop pain-free way to take diabetes medication
AI-based Computational Tools for Drug Delivery
COMMENTS
Drug delivery
Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within an organism, with the goal of achieving a therapeutic ...
The evolution of commercial drug delivery technologies
Research into non-invasive delivery systems has led to a better understanding of the kinetics of drug action, the biological barriers that prevent systemic drug access and the use of delivery ...
Why drug delivery is the key to new medicines
Metrics. Designing a new drug is not enough; it has to be delivered to its target, which can be achieved via a cornucopia of vehicles, from nanoparticles and microneedles to red blood cells and ...
Controlled Drug Delivery Systems: Current Status and Future Directions
Abstract. The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release.
Targeted Drug Delivery
Nanomedicine is an advanced version of Paul Ehrlich's "magic bullet" concept. Targeted drug delivery is a system of specifying the drug moiety directly into its targeted body area (organ, cellular, and subcellular level of specific tissue) to overcome the aspecific toxic effect of conventional drug delivery, thereby reducing the amount of drug required for therapeutic efficacy.
Nanoparticles in Drug Delivery: From History to Therapeutic
Abstract. Current research into the role of engineered nanoparticles in drug delivery systems (DDSs) for medical purposes has developed numerous fascinating nanocarriers. This paper reviews the various conventionally used and current used carriage system to deliver drugs. Due to numerous drawbacks of conventional DDSs, nanocarriers have gained ...
The Future of Drug Delivery
Drug delivery technologies have been proven to improve treatment outcomes in many ways, including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance, and enabling entirely new medical treatments. As the therapeutic landscape has evolved from small-molecule drugs to a new generation of therapeutics including proteins, peptides, monoclonal antibodies, nucleic acids ...
Drug Delivery
Drug Delivery publishes open access comprehensive peer-reviewed research articles on the development and application principles of drug delivery and targeting at molecular, cellular, and higher levels. Drug Delivery aims to serve both the academic and industrial communities and accepts research on the following topics: All aspects of drug delivery systems design and engineering for main routes ...
Recent progress in drug delivery
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. ... During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields ...
Nano based drug delivery systems: recent developments and future
Recently, there has been enormous developments in the field of delivery systems to provide therapeutic agents or natural based active compounds to its target location for treatment of various aliments [33, 34].There are a number of drug delivery systems successfully employed in the recent times, however there are still certain challenges that need to be addresses and an advanced technology ...
Drug Delivery Systems
Current research on drug delivery systems can be described in two broad categories: routes of delivery and delivery vehicles. Routes of Delivery. Medications can be taken in a variety of ways—by swallowing, by inhalation, by absorption through the skin, or by injection. Each method has advantages and disadvantages, and not all methods can be ...
PDF Drug Delivery Systems Fact Sheet
Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles, cargo, and targeting strategies. Routes of Delivery Medications can be taken in a variety of ways—by mouth, by inhalation, by absorption through
Nanofiber-Based Drug Delivery Systems: A Review on Its ...
Nanomaterials, especially nanofibers, hold considerable promise as drug delivery systems (DDS) by providing targeted administration of drugs due to their unique properties, such as large surface area, high porosity, and mechanical robustness. Nanofibers can be fabricated using various techniques lik …
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Drug Delivery and Translational Research is a dedicated platform for high-quality research focused on translational aspects of drug delivery/novel drug delivery systems. Explores the effect of rationally developed, effective delivery systems in different disease conditions. Considers preclinical and clinical data related to drug delivery systems.
Novel Drug Delivery Systems: An Important Direction for Drug Innovation
As research progresses, biomimetic drug delivery systems are poised to become ideal candidates for efficient and targeted drug delivery systems. 3. Coupling Targeted Drug Delivery Systems. In recent years, the field of drug delivery has witnessed remarkable advancements, particularly in the realm of targeted delivery technologies. Among these ...
Drug delivery to and through the skin
Drug delivery technology has advanced significantly over >50 years, and has produced remarkable innovation, countless publications and conferences, and generations of talented and creative scientists. However, a critical review of the current state-of-the-art reveals that the translation of clever and sophisticated drug delivery technologies into products, which satisfy important, unmet ...
Targeted drug delivery strategies for precision medicines
Drug delivery materials and approaches have now advanced to a point where they can enable the modulation of a drug's pharmacological parameters, without compromising the desired effect on ...
Advanced drug delivery 2020 and beyond: Perspectives on the future
The drug delivery system (DDS) is a "formulation or device that delivers an API in site-directed applications or provides timely (i.e., immediate, delayed, or sustained) release of the API. The system, on its own, is not pharmaceutically active, but improves the efficacy and/or safety of an API that it carries [ 2 ].".
Recent advances in polymeric drug delivery systems
Polymeric drug delivery systems have been achieved great development in the last two decades. Polymeric drug delivery has defined as a formulation or a device that enables the introduction of a therapeutic substance into the body. Biodegradable and bio-reducible polymers make the magic possible choice for lot of new drug delivery systems. The future prospects of the research for practical ...
Current landscape of mRNA technologies and delivery systems for new
Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects. In this regard, lipid nanoparticles have been successfully utilized to improve mRNA delivery and protect the cargo from extracellular degradation. Encapsulation in lipid nanoparticles was an ...
Polymeric Nanoparticles for Drug Delivery: Recent Developments and
The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led to an increasing interest in the development and optimization of drug-delivery systems. Polymeric nanoparticles stand out as a key tool to improve drug bioavailability or specific delivery at the site of action. The versatility of polymers makes them ...
Advanced drug delivery 2020 and beyond: Perspectives on the future
The drug delivery system (DDS) is a "formulation or device that delivers an API in site-directed applications or provides timely (i.e., immediate, delayed, or sustained) release of the API. The system, on its own, is not pharmaceutically active, but improves the efficacy and/or safety of an API that it carries [2].".
Microchip Based Isolation and Drug Delivery of Patient‐Derived
Extracellular vesicles (EVs) have demonstrated significant potential in drug delivery and anti-tumor therapy. Despite this promising strategy, challenges such as specific targeting, EVs purification persist. In this study, a personalized nanodrug delivery platform using patient-derived tumor EVs (PT-EVs) based on a microchip is presented.
The rise and rise of drug delivery
Nanoparticle delivery is an alternative to using liposomes as drug carriers, and nanotechnology is a burgeoning area of drug-delivery research. Nanoparticles are solid, colloidal particles that ...
The Role of Surface Energy and Wettability in Polymer-Based Drug
Additionally, the balance between hydrophilicity and hydrophobicity is essential for optimizing drug-polymer interactions, particularly in systems designed for sustained or targeted drug delivery. Advances in surface modification techniques have enabled precise control over these parameters, allowing for the customization of polymers to meet ...
Drug delivery system targets chemo-induced hearing loss
To create the drug delivery system, Agrahari and her research team carefully considered the route it would take to the inner ear and the obstacles it would encounter along the way. As a drug ...
Streamlining Drug Development and Improving Patient Care
As a result, the QM CoE is anticipated to help streamline drug development and accelerate the delivery of safe, effective, therapeutically optimized medicines to the public.
Drug delivery research
Twenty-five years ago, when particulate drug delivery systems were just beginning to emerge, Sven Frøkjær moved to Novo (now Novo Nordisk). His job: to set up a basic research unit focusing on ...
Research Effort Will Bring Personalized Medicine to Drug Prescriptions
A Columbia University-led multicenter research effort called IndiPHARM: individual metabolome and exposome assessment for pharmaceutical optimization will develop a platform and monitoring system to prevent unwanted interactions between medications and other environmental, genetic, and lifestyle factors, in order to optimize therapeutic efficacy. . IndiPHARM is supported by a $39.5 million ...
Drug delivery systems: An updated review
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. ... There has been extensive research on drug delivery by biodegradable polymeric devices ...
IMAGES
VIDEO
COMMENTS
Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within an organism, with the goal of achieving a therapeutic ...
Research into non-invasive delivery systems has led to a better understanding of the kinetics of drug action, the biological barriers that prevent systemic drug access and the use of delivery ...
Metrics. Designing a new drug is not enough; it has to be delivered to its target, which can be achieved via a cornucopia of vehicles, from nanoparticles and microneedles to red blood cells and ...
Abstract. The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release.
Nanomedicine is an advanced version of Paul Ehrlich's "magic bullet" concept. Targeted drug delivery is a system of specifying the drug moiety directly into its targeted body area (organ, cellular, and subcellular level of specific tissue) to overcome the aspecific toxic effect of conventional drug delivery, thereby reducing the amount of drug required for therapeutic efficacy.
Abstract. Current research into the role of engineered nanoparticles in drug delivery systems (DDSs) for medical purposes has developed numerous fascinating nanocarriers. This paper reviews the various conventionally used and current used carriage system to deliver drugs. Due to numerous drawbacks of conventional DDSs, nanocarriers have gained ...
Drug delivery technologies have been proven to improve treatment outcomes in many ways, including enhancing therapeutic efficacy, reducing toxicity, increasing patient compliance, and enabling entirely new medical treatments. As the therapeutic landscape has evolved from small-molecule drugs to a new generation of therapeutics including proteins, peptides, monoclonal antibodies, nucleic acids ...
Drug Delivery publishes open access comprehensive peer-reviewed research articles on the development and application principles of drug delivery and targeting at molecular, cellular, and higher levels. Drug Delivery aims to serve both the academic and industrial communities and accepts research on the following topics: All aspects of drug delivery systems design and engineering for main routes ...
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to desired tissues, organs, cells and subcellular organs for drug release and absorption through a variety of drug carriers. ... During 2015-2018, significant progress in the research on drug delivery systems has been achieved along with advances in related fields ...
Recently, there has been enormous developments in the field of delivery systems to provide therapeutic agents or natural based active compounds to its target location for treatment of various aliments [33, 34].There are a number of drug delivery systems successfully employed in the recent times, however there are still certain challenges that need to be addresses and an advanced technology ...
Current research on drug delivery systems can be described in two broad categories: routes of delivery and delivery vehicles. Routes of Delivery. Medications can be taken in a variety of ways—by swallowing, by inhalation, by absorption through the skin, or by injection. Each method has advantages and disadvantages, and not all methods can be ...
Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles, cargo, and targeting strategies. Routes of Delivery Medications can be taken in a variety of ways—by mouth, by inhalation, by absorption through
Nanomaterials, especially nanofibers, hold considerable promise as drug delivery systems (DDS) by providing targeted administration of drugs due to their unique properties, such as large surface area, high porosity, and mechanical robustness. Nanofibers can be fabricated using various techniques lik …
Drug Delivery and Translational Research is a dedicated platform for high-quality research focused on translational aspects of drug delivery/novel drug delivery systems. Explores the effect of rationally developed, effective delivery systems in different disease conditions. Considers preclinical and clinical data related to drug delivery systems.
As research progresses, biomimetic drug delivery systems are poised to become ideal candidates for efficient and targeted drug delivery systems. 3. Coupling Targeted Drug Delivery Systems. In recent years, the field of drug delivery has witnessed remarkable advancements, particularly in the realm of targeted delivery technologies. Among these ...
Drug delivery technology has advanced significantly over >50 years, and has produced remarkable innovation, countless publications and conferences, and generations of talented and creative scientists. However, a critical review of the current state-of-the-art reveals that the translation of clever and sophisticated drug delivery technologies into products, which satisfy important, unmet ...
Drug delivery materials and approaches have now advanced to a point where they can enable the modulation of a drug's pharmacological parameters, without compromising the desired effect on ...
The drug delivery system (DDS) is a "formulation or device that delivers an API in site-directed applications or provides timely (i.e., immediate, delayed, or sustained) release of the API. The system, on its own, is not pharmaceutically active, but improves the efficacy and/or safety of an API that it carries [ 2 ].".
Polymeric drug delivery systems have been achieved great development in the last two decades. Polymeric drug delivery has defined as a formulation or a device that enables the introduction of a therapeutic substance into the body. Biodegradable and bio-reducible polymers make the magic possible choice for lot of new drug delivery systems. The future prospects of the research for practical ...
Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects. In this regard, lipid nanoparticles have been successfully utilized to improve mRNA delivery and protect the cargo from extracellular degradation. Encapsulation in lipid nanoparticles was an ...
The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led to an increasing interest in the development and optimization of drug-delivery systems. Polymeric nanoparticles stand out as a key tool to improve drug bioavailability or specific delivery at the site of action. The versatility of polymers makes them ...
The drug delivery system (DDS) is a "formulation or device that delivers an API in site-directed applications or provides timely (i.e., immediate, delayed, or sustained) release of the API. The system, on its own, is not pharmaceutically active, but improves the efficacy and/or safety of an API that it carries [2].".
Extracellular vesicles (EVs) have demonstrated significant potential in drug delivery and anti-tumor therapy. Despite this promising strategy, challenges such as specific targeting, EVs purification persist. In this study, a personalized nanodrug delivery platform using patient-derived tumor EVs (PT-EVs) based on a microchip is presented.
Nanoparticle delivery is an alternative to using liposomes as drug carriers, and nanotechnology is a burgeoning area of drug-delivery research. Nanoparticles are solid, colloidal particles that ...
Additionally, the balance between hydrophilicity and hydrophobicity is essential for optimizing drug-polymer interactions, particularly in systems designed for sustained or targeted drug delivery. Advances in surface modification techniques have enabled precise control over these parameters, allowing for the customization of polymers to meet ...
To create the drug delivery system, Agrahari and her research team carefully considered the route it would take to the inner ear and the obstacles it would encounter along the way. As a drug ...
As a result, the QM CoE is anticipated to help streamline drug development and accelerate the delivery of safe, effective, therapeutically optimized medicines to the public.
Twenty-five years ago, when particulate drug delivery systems were just beginning to emerge, Sven Frøkjær moved to Novo (now Novo Nordisk). His job: to set up a basic research unit focusing on ...
A Columbia University-led multicenter research effort called IndiPHARM: individual metabolome and exposome assessment for pharmaceutical optimization will develop a platform and monitoring system to prevent unwanted interactions between medications and other environmental, genetic, and lifestyle factors, in order to optimize therapeutic efficacy. . IndiPHARM is supported by a $39.5 million ...
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. ... There has been extensive research on drug delivery by biodegradable polymeric devices ...